Scientists have discovered a previously undetected layer in the cornea, the clear window at the front of the human eye.The breakthrough, could help surgeons to dramatically improve outcomes for patients undergoing corneal grafts and transplants.The new layer has been dubbed the Dua’s Layer after the academic Professor Harminder Dua who discovered it.
Professor Dua, Professor of Ophthalmology and Visual Sciences at The University of Nottingham, said: “This is a major discovery that will mean that ophthalmology textbooks will literally need to be re-written. Having identified this new and distinct layer deep in the tissue of the cornea, we can now exploit its presence to make operations much safer and simpler for patients.
“From a clinical perspective, there are many diseases that affect the back of the cornea which clinicians across the world are already beginning to relate to the presence, absence or tear in this layer.”
Understanding the properties and location of the new Dua’s layer could help surgeons to better identify where in the cornea these bubbles are occurring and take appropriate measures during the operation. If they are able to inject a bubble next to the Dua’s layer, its strength means that it is less prone to tearing, meaning a better outcome for the patient.
The discovery will have an impact on advancing understanding of a number of diseases of the cornea, including acute hydrops, Descematocele and pre-Descemet’s dystrophies.
The scientists now believe that corneal hydrops, a bulging of the cornea caused by fluid build up that occurs in patients with keratoconus (conical deformity of the cornea), is caused by a tear in the Dua layer, through which water from inside the eye rushes in and causes waterlogging.
Publication: Harminder S. Dua, et al., “Human Corneal Anatomy Redefined : A Novel Pre-Descemet’s Layer (Dua’s Layer),” 2013, Ophthalmology; DOI: 10.1016/j.ophtha.2013.01.018,
Source: The University of Nottingham
No comments:
Post a Comment